This machine is suitable for medical, hygienic and restaurant business, for packing of alcoholic cotton cloth and sterilized tissue. It is incorporates across deviation correction device with two degrees of freedom and an intelligent longitudinal photoelectric trademark positioning system. It can perform automatic plying, cutting and filling of tissue; packing-making, binding, liquid-dripping, printing of production date and preset counting. Packs are made in two rows and are four-sideed bound.